Although I advocate donating to the Red Cross or another vetted organization directly to help with relief in Japan, I am also heartened by the efforts of artists to raise awareness and lend a hand.
Flavorwire has a great gallery of artists selling pieces to benefit relief efforts in the wake of the country's devastating earthquake and tsunami. The print above, designed by Max Erdenberger of W+K Studio, is $25, and 100% of the profits go to the Red Cross.